ABT-751
编号ABP000587
化学名称ABT-751
CAS141430-65-1
分子式C18H17N3O4S
分子量371.41
纯度 >99%
化学名称 : ABT-751
CAS : 141430-65-1
英文名称: ABT-751
英文同义词: N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide
溶解度:DMSO
储存条件:at -20
生物活性
ABT-751 is a bioavailable antimitotic sulfonamide agent that binds to the colchicine-binding site on beta-tubulin and inhibits the polymerization of microtubules, thereby preventing tumor cell replication.参考文献
[1] Hande KR et al. Clin Cancer Res. 2006 May 1;12(9):2834-40 [2] Segreti JA et al. Cancer Chemother Pharmacol. 2004 Sep;54(3):273-81 [3] Luo Y et al. Anticancer Drugs. 2009 Jul;20(6):483-92-
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