
化学名称 : RJR 2403 oxalate
CAS : 183288-99-5
英文名称: RJR 2403 oxalate
英文同义词: (E)-N-Methyl-4-(3-pyridinyl)-3-bute n-1-amine oxalate
同义词: (E)-N-Methyl-4-(3-pyridinyl)-3-bute n-1-amine oxalate
Solubility:Soluble to 100 mM in water
Storage:Desiccate at +4°C
Biologieal
A neuronal nicotinic receptor agonist, showing high selectivity for the α4β2 subtype (Ki values are 26 and 36000 nM for α4β2 and α7 receptors respectively). Active in vivo
Reference
Bencherif et al (1996) RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization. J.Pharmacol.Exp.Ther.
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