
化学名称 : GSK1292263/
CAS : 1032823-75-8
英文名称: GSK1292263/
英文同义词: GSK1292263
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabetes. In the intravenous glucose tolerance test, significant increases in the peak insulin response and insulin AUC(0-15 min) of 30-60% were reported in the GSK1292263 treatment group, compared with values in the vehicle control cohort. This insulin upregulation correlated with a significant increase in the glucose disposal rate.
参考文献
[1] http://professional.diabetes.org/News_Display.aspx?CID=82333&TYP=9
Prucalopride/
4-(2-(7-氨基-2-(呋喃-2-基)-[1,2,4]三唑并[1,5-a][1,3,5]三嗪-5-氨基)乙基)苯酚
139180-30-6
HU-308/HU 308
256934-39-1
氟替卡松丙酸酯
80474-14-2