化学名称 : 5-(4-氯苯基)-N-(3,5-二甲氧基苯基)-2-呋喃甲酰胺
CAS : 944261-79-4
英文名称: A-803467
英文同义词: 5-(4-Chlorophenyl)-N-(3,5-dimethoxy phenyl)-2-furancarboxamide
同义词: 5-(4-氯苯基)-N-(3,5-二甲氧基苯基)-2-呋喃甲酰胺
储存条件:Soluble to 100 mM in 1eq. HCl and to 100 mM in DMSO
生物活性
Highly selective α7 nAChR agonist (Ki = 26 nM) displaying negligible blockade of α1β1γδ and α3β4 nAChRs (IC50 ≥ 60 μM). Found to be inactive against a panel of 32 receptors at 1 μM, except 5-HT3 receptors (Ki = 930 nM).