化学名称 : 2-羟基-4-[[2-[[(4-甲基苯基)磺酰基]氧基]乙酰基]氨基]苯甲酸
CAS : 501919-59-1
英文名称: S31-201,NSC74859/
英文同义词: S31-201
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
SB743921 is a second generation, highly potent and active KSP inhibitor with a Ki of 0.1 nM for KSP (Eg5). It is 5-fold more potent against the ATPase activity of KSP than ispinesib. It has cytotoxic activity at less than 2 nM is a spectrum of tumor cell lines. It is negative in a mouse model of peripheral neuropathy in which paclitaxel is positive. [1]
参考文献