252935-94-7

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CHIR98014(CT98014)/

252935-94-7

编号ABP000489 化学名称CHIR98014(CT98014)/ 英文名称 CHIR98014(CT98014)/ 分子式C20H17Cl2N9O2 分子量486.314 纯度 98%

化学名称 : CHIR98014(CT98014)/

CAS : 252935-94-7

英文名称: CHIR98014(CT98014)/

英文同义词: N6-[2-((4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl)amino)- Ethyl]-3-nitro-2,6-pyridinediamine

生物活性

Very potent, selective, cell-permeable reversible inhibitors (INHs) of GSK-3; highly recommended tool.

参考文献

SE Nikoulina et al. Inhibition of Glycogen Synthase Kinase 3 Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle. Diabetes 2002, 51(7), 2190-2198. [online] DB Ring et al. Selective glycogen synthase kinase inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52: 588

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