
化学名称 : CHIR98014(CT98014)/
CAS : 252935-94-7
英文名称: CHIR98014(CT98014)/
英文同义词: N6-[2-((4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)-2-pyrimidinyl)amino)- Ethyl]-3-nitro-2,6-pyridinediamine
生物活性
Very potent, selective, cell-permeable reversible inhibitors (INHs) of GSK-3; highly recommended tool.
参考文献
SE Nikoulina et al. Inhibition of Glycogen Synthase Kinase 3 Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle. Diabetes 2002, 51(7), 2190-2198. [online] DB Ring et al. Selective glycogen synthase kinase inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo. Diabetes 52: 588
(R)-N-Boc-2-羟甲基吗啉
135065-71-3
7H-Pyrrolo[1,2-c]imidazol-7-one/5,6-dihydro-, hydrobromide (1:1)
272438-84-3
乙酰苯胺
103-84-4
MLN9708
1201902-80-8