198904-31-3

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Atazanavir(BMS-232632)/Reyataz

198904-31-3

编号ABP000606 化学名称Atazanavir(BMS-232632)/Reyataz 英文名称 Atazanavir(BMS-232632)/Reyataz MDL: MFCD08435966 分子式C38H52N6O7 分子量704.864 纯度 99%

化学名称 : Atazanavir(BMS-232632)/Reyataz

CAS : 198904-31-3

英文名称: Atazanavir(BMS-232632)/Reyataz

英文同义词: 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3s,8s,9s,12s)-2,5,6,10,13-pentaazatetradecanedioic acid;ATAZANAVIR

同义词: 3,12-Bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, 1,14-dimethyl ester, (3s,8s,9s,12s)-2,5,6,10,13-pentaazatetradecanedioic acid;ATAZANAVIR

Storage:at -20℃ 2 years

Biologieal

Atazanavir (Reyataz, BMS-232632) is an antiretroviral drug of the protease inhibitor (PI) class. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Atazanavir is distinguished from other PIs in that it can be given once-daily (rather than requiring multiple doses per day) and has lesser effects on the patient's lipid profile (the amounts of cholesterol and other fatty substances in the blood). Like other protease inhibitors, it is used only in combination with other HIV medications. [1]

Reference

P Pyrko. HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress. Cancer Research 2007, 67, 10920

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