1628208-23-0
编号ABP020270
化学名称CPI-455
英文名称 CPI-455
分子式C16H14N4O
分子量278.31
纯度 NLT 98%
化学名称 : CPI-455
CAS : 1628208-23-0
英文名称: CPI-455
英文同义词:
CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.
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