化学名称 : 普拉格雷
CAS : 150322-43-3
英文名称: Prasugrel/Effient
英文同义词: PRASUGREL
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
Prasugrel is a novel platelet inhibitor used for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndrome who are to be managed with PCI. [1]
Prasugrel reduces the aggregation ("clumping") of platelets by irreversibly binding to P2Y12 receptors. In rat platelets, prasugrel AM inhibited in vitro platelet aggregation induced by ADP (10 μm) with an IC50 value of 1.8 μm.
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