146426-40-6

溶解度:Unknown

储存条件:at -20℃ 2 years

生物活性

AT7519 is a novel small molecule multi-cyclin-dependent kinase inhibitor. It selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are serine/theronine kinases involved in regulation of the cell cycle and may be overexpressed in some types of cancer cells. [1][2]

参考文献

[1] Santo L et al. Oncogene. 2010 Apr 22;29(16):2325-36