112093-28-4

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Z-Endoxifen

112093-28-4

编号ABP027358 化学名称Z-Endoxifen 英文名称 Z-Endoxifen MDL: MFCD09840374 分子式C25H27NO2 分子量373.49 纯度 NLT 98%

化学名称 : Z-Endoxifen

CAS : 112093-28-4

英文名称: Z-Endoxifen

英文同义词:

Endoxifen is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα). Endoxifen inhibits hERG tail currents at 50 mV in a concentration-dependent manner with IC50 values of 1.6 μM.
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