化学名称 : 溴吡斯的明
CAS : 101-26-8
英文名称: Pyridostigmine Bromide/Mestinon
英文同义词: PYRIDOSTIGMINE BROMIDE
溶解度:Unknown
储存条件:at -20℃ 2 years
生物活性
Pyridostigmine Bromide(Mestinon) is a parasympathomimetic and a reversible cholinesterase inhibitor. Pyridostigmine Bromide inhibits acetylcholinesterase in the synaptic cleft, thus slowing down the hydrolysis of acetylcholine. It is a quaternary carbamate inhibitor of cholinesterase that does not cross the blood-brain barrier, and it is taken daily in anticipation of an attack, which carbamylates about 30% of peripheral cholinesterase enzyme. The carbamylated enzyme eventually regenerates by natural hydrolysis and excess ACh levels revert to normal. [1]
参考文献
[1] http://en.wikipedia.org/wiki/Pyridostigmine