101-26-8

溴吡斯的明

101-26-8

编号ABP000290 化学名称溴吡斯的明 英文名称 Pyridostigmine Bromide/Mestinon MDL: MFCD00079283 分子式C9H13N2O2.Br 分子量261.118 纯度 >99%

化学名称 : 溴吡斯的明

CAS : 101-26-8

英文名称: Pyridostigmine Bromide/Mestinon

英文同义词: PYRIDOSTIGMINE BROMIDE

溶解度:Unknown

储存条件:at -20℃ 2 years

生物活性

Pyridostigmine Bromide(Mestinon) is a parasympathomimetic and a reversible cholinesterase inhibitor. Pyridostigmine Bromide inhibits acetylcholinesterase in the synaptic cleft, thus slowing down the hydrolysis of acetylcholine. It is a quaternary carbamate inhibitor of cholinesterase that does not cross the blood-brain barrier, and it is taken daily in anticipation of an attack, which carbamylates about 30% of peripheral cholinesterase enzyme. The carbamylated enzyme eventually regenerates by natural hydrolysis and excess ACh levels revert to normal. [1]

参考文献

[1] http://en.wikipedia.org/wiki/Pyridostigmine

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