Compound 401
Cat.No.ABP025815
Chemical NameCompound 401
CAS168425-64-7
MDL: MFCD10568147
MolFormulaC16H15N3O2
MolWeight281.31
Purity NLT 98%
Chemical Name : Compound 401
CAS : 168425-64-7
Compound 401 is a cell-permeable pyrimido-isoquinolinone compound that acts as a potent, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 280 nM) with ~19-fold selectivity over mTOR (FRAP) (IC50 = 5.3 μM).
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