CPI-455
Cat.No.ABP020270
Chemical NameCPI-455
CAS1628208-23-0
MolFormulaC16H14N4O
MolWeight278.31
Purity NLT 98%
Chemical Name : CPI-455
CAS : 1628208-23-0
CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.
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