JNJ 5207852 dihydrochloride

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JNJ 5207852 dihydrochloride

JNJ 5207852 dihydrochloride

Cat.No.ABP019725 Chemical NameJNJ 5207852 dihydrochloride CAS398473-34-2 MDL: MFCD19690931 MolFormulaC20H34Cl2N2O MolWeight389.40 Purity NLT 98%

Chemical Name : JNJ 5207852 dihydrochloride

CAS : 398473-34-2

JNJ-5207852 is a selective, non-imidazole histamine H3R antagonist with high affinity at the rat (pKi = 8.9) and human (pKi = 9.24) H3 receptors.In rodents, 1-10 mg/kg JNJ-5207852 administered subcutaneously increases time spent awake and decreases REM sleep and slow-wave sleep.
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