Tenofovir,TDF,PMPA/

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Tenofovir,TDF,PMPA/

Tenofovir,TDF,PMPA/

Cat.No.ABP000917 Chemical NameTenofovir,TDF,PMPA/ CAS147127-20-6 MDL: MFCD00943794 MolFormulaC9H14N5O4P MolWeight287.215 Purity >99%

Chemical Name : Tenofovir,TDF,PMPA/

CAS : 147127-20-6

Synonyms: TENOFOVIR

Solubility:DMSO

Storage:at -20℃ 2 years

Biologieal

Previously the IN substitutions V75I, Q148R, V151I, and G163R were reported as being associated with BMS-707035 resistance [48] , although no indication was given as to the resistance severity associated with each substitution. BMS-707035 is an HIV-1 integrase (IN) inhibitor. BMS-707035 was scheduled to be evaluated in a Phase II study to assess the antiretroviral activity, safety, pharmacodynamics, and pharmacokinetics in 50 HIV-infected subjects using a 10-day randomized, double-blind, placebo-controlled, ascending multiple-dose study design

Reference

Laith Q Al-Mawsawi et al. Expert Opinion on Emerging Drugs. 2008 June;13(2):213-225

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