Chemical Name : SU-11274/SU11274,PKI-SU11274
CAS : 658084-23-2
溶解度:Soluble in DMSO 10 mg/ml at 60
储存条件:Store at -20°C
生物活性
Selective inhibitor of MET tyrosine kinase activity (IC50 = 0.01 μM in vitro). Reduces cell growth in a dose-dependent manner; induces cell cycle arrest and apoptosis. Abrogates cell motility and migration in vitro and tumor angiogenesis in vivo.