856243-80-6

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WP1130

856243-80-6

Cat.No.ABP000853 Chemical NameWP1130 MolFormulaC19H18BrN3O MolWeight384.27 Purity >99%

Chemical Name : WP1130

CAS : 856243-80-6

Synonyms: (2E)-3-(6-Bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-2-propenamide

Solubility:DMSO

Storage:at -20℃ 2 years

Biologieal

FG-4592, received Clinical Trial Application (CTA) approval from the Chinese State Food and Drug Administration (SFDA) to commence clinical development for the treatment of anemia associated with chronic kidney disease (CKD) in the People's Republic of China. FG-4592 is a first-in-class hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor (PHI) entering Phase 2b clinical development in the US and Europe for the treatment of CKD anemia. SFDA approved protocols for both Phase 1 and 2 studies. The first of these studies of FG-4592 in China will begin in the fourth quarter of 2010.

Reference

FG-4592 oral anemia therapy receives CTA approval from SFDA

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