55778-02-4

WZ811 is a novel small molecular and potency CXCR4 antagonist with EC50 WZ811 is a novel small molecular and potency CXCR4 antagonist with EC50 of 0.3 nM. IC50 Value: 0.3 nM(EC50) Target: CXCR4 in vitro: WZ811 efficiently inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cyclic adenosine monophophate (cAMP) levels (EC50 = 1.2 nM) and SDF-1 induced Matrigel invasion (EC50 = 5.2 nM). in viv