371980-98-2
371980-98-2
Cat.No.ABP000442
Chemical NameSB 612111 hydrochloride
MolFormulaC24H30Cl3NO
MolWeight454.86
Purity 97%
Chemical Name : SB 612111 hydrochloride
CAS : 371980-98-2
Synonyms: 7-[[4-(2,6-Dichlorophenyl)-1-piperi dinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzo cyclohepten-5-ol hydrochloride
Storage:Store at -20°C
Biologieal
Selective NOP receptor antagonist (Ki values are 0.33, 57.6, 160.5 and 2109 nM for NOP, μ-, κ- and δ-receptors respectively). Antagonizes the pronociceptive action of nociceptin (Cat. No. 0910) in an acute pain model. Potentiates the action of morphine in morphine-tolerant animals and blocks hyperalgesia in an inflammatory pain model.-
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