Home / Products / Inhibitors / MEK inhibitor / 167869-21-8


Cat.No.ABP000927 Chemical NamePD-98059/PD98059/ MolFormulaC16H13NO3 MolWeight267.2793 Purity >99%

Chemical Name : PD-98059/PD98059/

CAS : 167869-21-8

Synonyms: 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

Solubility:Soluble to 100 mM in DMSO

Storage:Store at +4°C


Selective fatty acid amide hydrolase (FAAH) inhibitor (Ki = 0.23 μM). Reduces inflammatory pain via a cannabinoid receptor-dependent mechanism. Highly efficacious and selective in vivo. Displays no activity at FAAH-2 (IC50 >10 μM).


Ahn et al (2009) Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain. Chem.Biol. 16 411. Ahn et al (2009) Fatty acid amide hydrolase as a potential therapeutic target for the treatment of pain and CNS disorders. Expert Opin.Drug Discov. 4 763.