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Cat.No.ABP000284 Chemical NameMK-5172/MK5172 MDL: MFCD17215202 MolFormulaC29H38N4O7 MolWeight554.64 Purity >98%

Chemical Name : MK-5172/MK5172

CAS : 1206524-85-7

Synonyms: MK-5172

Storage:-20℃ 2 years


MK-5172 is a novel NS3/4, a protease inhibitor for chronic HCV infection (Enzyme Ki for genotype1b, 2a, 2b and 3a at 0.02, 0.15, 0.02 and 0.7 nM, respectively). This agent has an attractive preclinical profile including high potency in vitro, significant liver exposure upon oral dosing, and potent inhibitory activity against viral variants that are resistant to other protease inhibitors in development. MK-5172 has also demonstrated anti-viral efficacy in a chimpanzee model of chronic HCV infection. [1, 2]


[1] http://www.natap.org/2010/EASL/EASL_38.htm